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This transgene consists of a 6.5 kb genomic fragment upstream of the murine Pax6 gene, an nlsCre, an IRES, EGFP, and a polyadenylation signal. The Pax6 promoter fragment drives expression of Cre and GFP in the surface ectoderm, developing lens, cornea, and pancreas in transgenic mice. (J:65765)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
