A floxed neomycin resistance gene was introduced in intron 2 and a single loxP site about 1 kb downstream from exon 3 by homologous recombination; transient expression of Cre recombinase in ES cells excised the neo gene, leaving exon 3 flanked by single loxP sites. (J:90558)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count