All four heavy chain J elements were replaced with a neo and a rearranged heavy chain VDJ region for an antibody specific for hapten (4-hydroxy-3-nitrophenyl) acetyl (NP). Southern blot confirmed recombination. Flow cytometry confirmed expression of the inserted VDJ region. (J:33628)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count