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An 11 kb segment of the gene including exons 1 and 2 and encoding amino acids 2 to 123 was replaced with a lacZ/neo cassette. The cassette was fused in frame. Recombination was confirmed by Southern blot and PCR and RT-PCR indicated absence of gene expression in mutant mice. (J:90843)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
