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EN
Homologous recombination incorporated serine to alanine substitutions in the MAPK-consensus phosphorylation sites (p.S187A, p.S195A, p.S206A, p.S214A) and two conserved phosphoserines in exon 3 (p.(S209_S210delinsAA)). Western blot analysis of MEF nuclear extracts demonstrated the mutant protein was expressed at similar levels as that of wild-type. (J:90769)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
