The entire open reading frame of mouse Tbx18 was fused to a mesodermal specific promoter containing a 1495 bp mesodermal element from the 5' untranslated region of the Dll1 gene fused to the Dll1 minimal promoter. Two lines were generated, Tg(Dll1-Tbx18)2Akis and Tg(Dll1-Tbx18)20Akis, with the latter showing a more severe homozygous phenotype. The mesodermal specific promoter was first described in J:63760 (J:63760, J:90513)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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