A neo gene was inserted into exon 1 via homologous recombination disrupting the first coding exon and exon splice donor site. Immunoblotting of B-cell lysates after immunization confirmed the absence of protein expression in homozygous mice. Expression of clustered and related Rgs genes was unaffected. (J:90780)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count