A loxP site was inserted upstream of exon 2, and a neo-thymidine kinase selection cassette with a 3' loxP site was inserted downstream of exon 2. Southern blot and RT-PCR indicate presence of recombinant transcript. (J:90390)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count