The transgene consists of 3 kb of 5' flanking sequence, exon 1 (comprising additional 5' untranslated sequence), and the first intron, including the 3' splice site, from the human beta-actin gene; the v-erbA oncogene, which comprises the avian erythroblastosis retroviral gag gene followed by a mutated chicken thryroid receptor hormone alpha gene; and the SV40 polyadenylation signal. (J:90554)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count