The transgene consists of 3 kb of 5' flanking sequence, exon 1 (comprising additional 5' untranslated sequence), and the first intron, including the 3' splice site, from the human beta-actin gene; the v-erbA oncogene, which comprises the avian erythroblastosis retroviral gag gene followed by a mutated chicken thryroid receptor hormone alpha gene; and the SV40 polyadenylation signal. (J:90554)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x CBA/J)F1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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