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This allele confers susceptibility to atherosclerosis and decreased HDL cholesterol levels on an atherogenic diet compared to BALB/cJ, C3H/HeJ, and SPRET/EiJ. This allele confers increased aortic lesion area in females on a high fat diet compared to C3H/HeJ. (J:8735, J:140288)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
