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EN
The transgene comprises the 5' regulatory region and the first four codons of the beta-2 microglobulin gene followed, in-frame, by the beta-galactosidase (lacZ) gene and nuclear localization sequences and, in the same transcriptional orientation, the Herpes simplex virus thymidine kinase/neomycin resistance fusion gene. Beta-galactosidase is expressed under control of the beta-2 microglobulin promoter. (J:79264)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
