The transgene comprises a cDNA encoding the extracellular domain of IL1RL1 fused to the Fc portion of human IgG gamma 1 under control of the liver-specific promoter of the human SERPIN1A gene. The soluble fusion protein is secreted into the serum. (J:63507)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count