Sequence encoding nls-cre was adjoined to Vav1 promoter sequence. Cre activity was detected in hematopoietic cells including greater than 99% of neutrophils, macrophages, T cells and greater than 90% of B cells and nucleated erythroid cells. Activity was also detected in endothelial cells, and testes. (J:89785)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count