A single loxP site remained in place of a genomic fragment encompassing the entire coding region (exons 2 and 3) after floxed selection cassette was inserted and subsequntly removed via homologous and cre-mediated recombination. Neither transcript nor protein was detected in various organs or MEFs, respectively. (J:89563)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count