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Exons 2 - 4 were replaced with LacZ and a nuclear localization signal via homologous recombination. Protein and mRNA expression were absent from white adipose tissue. Immunoblot analysis and radioimmunoassay also confirmed the absence of dirculating protein. LacZ expression is detected in white adipose tissue. (J:90033)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
