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A portion of exon 1 including the ATG start site was replaced with a cassette containing an IRES element, a tau-GFP fusion gene, a loxP site, a PGK-1 promoter, a neomycin resitance gene, a PGK-1 polyA tail and a second loxP site. Western blot analysis confirmed the absence of protein in spinal cords from homozygous null mice. The tau-GFP fusion protein is expressed from the Robo3 promoter. (J:89438)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
