A human OTX1 cDNA flanked by the Otx2 5' and 3' UTR's replaced all the coding sequence and introns. Only 50 bp of poladenylation signal is duplicated in this allele. This allele expresses the human OTX1 protein under Otx2 transcriptional control. (J:89361)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count