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Cre recombinase and neomycin resistance genes replaced an 82 bp exonic sequence encoding the start codon and the following 69 bp of intronic sequence. In situ hybridization demonstrated the absence of normal RNA and Western blot confirmed absence of normal protein from mutant mice. (J:89407)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
