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Sequence encoding cre recombinase was adjoined to 2.3 kb of the Col1a1 promoter. The endogenous Col1a1 promoter is active in osteoblasts throughout their differentiation and, accordingly, expression of cre recombinase was detected exclusively in bone. Cytogenetic mapping indicates that the transgene integrated on chromosome 14qE2-4. (J:77071, J:165282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
