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A lacZ and neo cassette was inserted into the first exon, deleting 310 bp of exon 1, spanning the translation initiation site and the first 257 bp (85 codons). Lack of transcript was confirmed by Northern blot of mutant heart, kidney and lung. Beta-galactosidase was expressed from this allele under the control of the endogenous promoter. (J:89618)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
