Floxed exons 4-7 in Mapk7tm1Jdl were removed by Cre-mediated recombination, leaving a single loxP site. These exons encode for the kinase domain and the unique C-terminal nonkinase region of the protein. Western blot of homozygous mutant livers confirmed absence of protein. (J:89215)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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