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This transgene contains the simian virus 40 early gene promoter (viral) and an allele of the human Harvey rat sarcoma virus oncogene that contains a deletion of exon 1 and part of intron 1, and carries an activating point mutation in codon 12 (Gly12Val). The construct also contains mouse immunoglobulin heavy chain complex enhancer sequences. (J:46455)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
