The human two immunoglobulin-loop isoform of FGFR1 bearing the K656E mutation and an artificial FLAG epitope was inserted downstream of the ARR2PB composite promoter that consists of a minimal probasin promoter that was modified to contain two androgen response elements. RT-PCR analysis showed that transgene expression is limited to the prostate gland. (J:87067)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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