The human two immunoglobulin-loop isoform of FGFR1 bearing the K656E mutation and an artificial FLAG epitope was inserted downstream of the ARR2PB composite promoter that consists of a minimal probasin promoter that was modified to contain two androgen response elements. RT-PCR analysis showed that transgene expression is limited to the prostate gland. (J:87067)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count