This transgene contains the mouse mammary tumor virus promoter and a 4.6 kb cDNA from the rat avian erythroblastosis B2 oncogene. The activated form of the gene is used in this construct, which differs from the wild-type allele by a point mutation, Val664Glu. (J:72082)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count