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Sequence encoding cre recombinase was adjoined to Kdr promoter/enhancer sequence to drive expression of cre in the endothelial cells of the embyronic vascular system. The construct consisted of 939 bp of Kdr promoter sequence fused to cre sequence followed by a polyA signal and 2.3 kb of the first intron of Kdr. Cre-mediated recombination of a reporter transgene was observed in the embryonic vasculature at E11.5. (J:88924)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
