Exons 5 and 6, which encode the F-box, were deleted via cre mediated recombination of loxP sites inserted in introns 4 and 6. An frt-flanked neo cassette remained in intron 4 after the excision of the floxed fragment. (J:88903)
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Exons 5 and 6, which encode the F-box, were deleted via cre mediated recombination of loxP sites inserted in introns 4 and 6. An frt-flanked neo cassette remained in intron 4 after the excision of the floxed fragment. (J:88903)