These transgenic mice express the tetracycline-inhibitable transcription factor (tTA) under the control of beta actin promoter. There is a floxed translational stop codon between the promoter and the tTA coding sequence. The tTA protein is only produced in cells where cre recombinase was expressed. (J:77659)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count