The transgenic construct consisted of cDNA encoding cre recombinase adjoined to the mouse Krt2-6a promoter. Cre-mediated recombination was observed in the companion cell layer of hair follicles, a discrete cell population located between the inner and outer root sheaths. With retinoic acid treatment, the expression domain is expanded to the interfollicular basal and outer root sheath cells. (J:88795)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CBA and C57BL/6J
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top