LoxP sites were inserted upstream of exon 3 and downstream of exon 6. In addition, an FRT flanked PGK-neo cassette was inserted in intron 6. An frt-flanked neomycin selection cassette was removed by crossing mice carrying Mybtm1Jof to FlpE expressing mice, leaving loxP sites flanking exons 3-6. (J:85344)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count