Multiple copies (>3) of a non-expressing transgene inserted into the first intron of the gene. In total RNA samples from newborn mice, no transcript of the endogenous gene was detected in homozygotes and approximately 45% reduction was seen in heterozygotes. (J:123744)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count