LoxP sites flanking exons 1 and 2 were introduced to the gene by homologous recombination. The floxed region includes the entire coding region. The targeted allele was verified by Southern blot analysis. (J:88668)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count