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A neomycin cassette was inserted into the open reading frame disrupting this gene. Northern analysis of RNA isolated from neutrophils from homozygotes demonstrated that no detectable transcript is produced from this allele. No antagonist binding was detectable in peritoneal macrophages or lung tissues from homozygotes. (J:88505)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
