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The first ATG codon of the gene was mutated to an EcoRV site, with an enhanced GFP gene and a neomycin resistance cassette being inserted into the EcoRV site. Gene inactivation was confirmed by a lack of product from RT-PCR of Peyer's patch RNA. GFP expression was observed in B cells expressing IgA, and in other leukocyte subsets including neutrophils. (J:69621, J:140728)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
