A gene trap vector inserted into the endogenous gene such that the beta-galactosidase and neomycin genes were fused to the expressed mRNA at position 1149. Beta-galactosidase expression was noted in a similar pattern to the wild-type mRNA. RT-PCR analysis indicated that a low level of wild-type transcript was still expressed from this allele, suggesting that this mutation is a hypomorph. (J:69466)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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