A spontaneous mutant identified in the Genetics Laboratory at Faculty of Veterinary Medicine, Iasi, Romania, this mutant was determinied to be an allele at the fz locus via complementation analysis. Reverse transcription-polymerase chain reaction (RT-PCR) analysis of mutant DNA detected an excessively long mRNA that was shown to be the product of abnormal RNA splicing consequent to insertion of a class II retrotransposon into the third intron. (J:125551)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Swiss albino
Spontaneous
Transposon insertion
Recessive
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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