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A loxP site was inserted upstream of exon 1 and a floxed neomycin cassette was placed downstream of exon 4. The neomycin gene was subsequently excised from properly targeted ES cells by transient transfection with a cre expressing plasmid. This resulted in all four exons being flanked by two loxP sites. (J:87435)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
