Exons 1b, 2, and 3 were replaced by a loxP site, an Fgf3 cDNA and a floxed neomycin resistance gene. Heterozygous mice were then mated to deleter-cre mice to remove the cDNA and neomycin insert. Absence of transcripts was confirmed by RNA in situ hybridization. (J:87221)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
3
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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