A portion of first coding exon, including the start codon and the coding region, was replaced with a lacZ and neo cassette inserted by homologous recombination. RT-PCR analysis of homozygous mutant embryos indicated that no normal transcript was produced from this loci. LacZ transcript was detected by RT-PCR analysis of mutant embryos. (J:87394)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
3
21

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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