Log In|Sign Up
EN
This allele is a single base change from T to A in the exon 4 splice donor. This results in a primary product in which exon 4 is deleted as well as a minor product with both exons 4 and 5 deleted. In either case, a frame shift results and mRNA transcript cannot be detected by whole mount in situ hybridization. An mRNA that was approximately 70 bases shorter than normal could be detected by RT-PCR but only weakly. (J:87046)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
