This allele was derived from Hcn4tm1Jsr by breeding chimerics for that allele to Cre deleter mice expressing Cre in the gametes. This results in excision of exon 4 which encodes the pore region and transmembrane segment S6. Absence of protein product was demonstrated immunologically. (J:86988)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count