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Two loxP sites were inserted so as to flank the two exons encoding the extracellular Ig-like domains as well as an FRT enclosed neomycin resistance gene (Icosltm2Cdon. These two exons and the neomycin gene were subsequently removed by crossing F1 mice with a cytomegalovirus-cre transgenic mouse. Absence of protein product was confirmed immunologically. (J:86697)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
