The frt flanked neomycin selection cassette was excised from Ppargtm1Auw via FLP mediated recombination. The proline to alanine missense mutation at codon 12 (exon B) was left intact. The levels of both Pparg1 and Pparg2 transcript in homozygous mutant mice did not significantly differ from those of wild-type. (J:86705)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Nucleotide substitutions
--
1
10
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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