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Exon 2 was disrupted by the insertion of a neomycin selection cassette. Protein was undetected by immunohistochemical analysis of homozygous mutant lung, kidney, liver, and spleen tissues. The absence of protein was further confirmed by flow cytometry, which showed no protein expression on the surface of homozygous mutant thymocytes, T or B lymphocytes, or myeloid cells. (J:54748)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
