Insertion of a neomycin resistance cassette into exon 2 disrupted the Kcnq1 gene. Northern blot analysis demonstrated that no detectable transcript was expressed in hearts of homozygous mice. (J:67873)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count