Log In|Sign Up
EN
Sequencing of the Rpe65 gene of C57BL/6-Tyrc-2J/J revealed a cytosine to adenosine polymorphism in codon 450, resulting in a leucine to methionine substitution (L450M). Later studies show that this variant is presnt in all C57BL/6J mice. (J:62583, J:86186)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
