Exon 1 was replaced with a cassette containing lacZ and neo. Transcript was undetected in homozygous mutant mice by Northern blot analysis of RNA obtained from the small intestine and the colon. The expression pattern of lacZ was realized by X-gal staining and was similar to that of the endogenous gene. (J:86267)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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