Exon 1 was disrupted by the insertion of a neomycin selection cassette. Neither normal transcript nor aberrant splice products were detected by RT-PCR analysis. Protein was undetected by Western blot analysis of extracts of homozygous mutant splenic B cells. (J:86182)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count