A loxP flanked neomycin selection cassette was inserted 100 bp upstream of the Jlambda1 recombination signal sequence. In addition, two point mutations were introduced that altered codon 154 of the Clambda1 region from one that encodes glycine to one encoding serine (G154S). (J:68144)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion, Nucleotide substitutions
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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