Log In|Sign Up
EN
This phenotypic mutation was identified in an ENU mutagenesis screen at the MRC Mammalian Genetics Unit, Harwell, UK. A point mutation in Zfhx3 was identified in exon 9, resulting in a G to T transversion at position 6620 and a substitution of a phenylalanine for a valine at residue 1963 (V1963F) in a highly conserved region just upstream of the 17th zinc-finger motif. This appears to be a gain of function allele. (J:223990)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
