LoxP sites were inserted in introns 3 and 6 thus flanking exons 4 through 6. In addition, a Hygro selection cassette was placed in intron 3 between the loxP site and the start of exon 4. (J:85481)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count